Mandibular Trauma and Antibiotic Use (MANTRA)

Study Leads - Basim Dawoud and Becks Exley

Consultant Advisor - Panos Kyzas

This project was initiated in 2020, and aims to establish the risks and benefits of treating patients with mandible fractures on an outpatient basis. There is variation in practice, with some centres discharging all mandible fractures and carrying out ORIF electively and others admitting for IV antibiotics and emergent treatment. Patient preference, health economics and patient outcomes may vary between these two treatment algorithms. This project aims to use an initial survey of practice, followed by a national prospective audit, to determine current practice and inform design of a trial. 

February 2021

With over 200 records so far, the MANTRA snapshot audit is off to a flying start!! More units are reaching the required 5 records to be cited in future papers, and we are in the process of identifying the high performing units which will be invited to co-author. It’s not too late to sign your unit up (check the map to see if your unit is involved), and you can add all fractured mandibles which your unit has seen since 3rd December 2020. 


November 2020

Preliminary results of MTReC UK wide survey show variation exists across the UK with regard to use of antibiotics when managing mandibular fractures.  


Collaborators have been contacted and the process of the registering the study locally and setting up access to REDCap has begun.

If you have been assigned as lead collaborator in your unit you will be require the following resources.

Link to register your local unit

The collaborator information pack

Presentation to propose study to your department

Guide to help you add data to REDCap


  1. B.E.S.Dawoud, S.Kent, A.Henry, J.Wareing, H.Chaudryeon, Panayiotis Kyzasg. The use of antibiotics in traumatic mandibular fractures: A systematic review and meta-analysis. British Journal of Oral and Maxillofacial Surgery. Available online 15 March 2021. DOI:

The Maxillofacial Trainee Research Collaborative

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